Non-24-Hour Sleep-Wake Disorder
National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Non-24-Hour Sleep-Wake Disorder is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
- free-running disorder
- circadian rhythm sleep disorder, free-running type
- hypernychthemeral syndrome
- non-24-hour disorder
- non-24-hour sleep-wake syndrome
- non-24-hour sleep-wake cycle disorder
Non-24-hour sleep-wake disorder (N24) is a circadian rhythm sleep disorder in which an individual's biological clock fails to synchronize to a 24-hour day. Instead of sleeping at roughly the same time every day, someone with N24 will typically find their sleep time gradually delaying by minutes to hours every day. They will sleep at later and later clock times until their sleep periods go all the way around the clock. (In extremely rare cases the sleep rhythm will gradually advance rather than delay.) Patients' cycles of body temperature and hormone rhythms also follow a non-24-hour rhythm. Attempts to fight against this internal rhythm and sleep on a normal schedule result in severe and cumulative sleep deprivation.
N24 occurs in roughly 50% of completely blind people but also occurs in an unknown number of sighted people.
Circadian Sleep Disorders Network
4619 Woodfield Rd.
Bethesda, MD 20814
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The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.
It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
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Last Updated: 3/26/2013
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