| Contact Information: |
| Phone: (603) 650-6633 |
| Fax: (603) 650-7791 |
| Email: not given |
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| Institution Affiliations: |
| Associate Professor of Medicine (Hematology/Oncology) & of Pharmacology and Toxicology |
| Department of: MEDICINE |
| Section: Clinical Pharmacology |
| Specialty: Medical Oncology |
| Joined Staff: 1998 |
| Cancer Center Membership: |
| Clinical Interests: |
| Gastrointestinal Cancer |
| SARCOMA |
| Early Phase Clinical Trials |
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| Board Certified: |
| Medical Oncology 1991 2001 |
| Internal Medicine 1988 |
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| Northeastern Ohio Universities College of Medicine, Rootstown, OH 1985 |
| Michael Reese Hospital & Medical Center, Chicago, IL, (Oncology) 1985-88 |
| Fox Chase Cancer Center, Philadelphia, PA, (Medical Oncology) , Senior Research Fellow 1991-92
1988-92 |
| Dr. Perez did his undergraduate work at Kent State University and he received his M.D. in 1985 from Northeastern Ohio Universities College of Medicine. Dr. Perez completed his residency at the Michael Reese Hospital and Medical Center in 1988, and in 1992 he completed his oncology fellowship from Fox Chase Cancer Center. From 1992 to January 1998 Dr. Perez was an Assistant Professor of Medicine at the Roswell Park Cancer Center. He joined the DMS in February 1998 as an Associate Professor of Medicine and oncologist for the GI Program. |
| Dr. Perez's areas of research have included: molecular determinants of sensitivity to anticancer drugs (particularly cisplatin, currently focusing on P53 and BCL2-family interactions), early drug development (primarily platinum-based phase I trials), detection of minimal residual melanoma in peripheral blood by RT-PCR, and deletion of specific sequences by thermostable DNA polymerases. |
| Pendyala L, Perez R, Weinstein A, Zdanowicz J, and Creaven P. Effect of glutathione depletion on the cytotoxicity of cisplatin and oxaliplatin in a human melanoma cell line. Cancer Chemother Pharmacol, 40:38-44, 1997. |
| Schwartz G, Pendyala L, Kindler H, Meropol N, Perez R, Raghavan D, and Creaven PJ. The clinical development of paclitaxel and the paclitaxel/carboplatin combination. Eur J Cancer, 34:1543-1548, 1998. |
| Perez R, and Zhang P. Detection of EWS-WT1 fusion mRNA in ascites of a patient with intra-abdominal desmoplastic small round cell tumor. Human Pathol, 1999. |
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Mailing Address:
Norris Cotton Cancer Center
Dartmouth-Hitchcock Medical Center
One Medical Center Drive
Lebanon, NH 03756
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